采矿方法的选择对于矿山企业的生存与发展至关重要，特别是对于矿体开采技术条件较为复杂的矿山更为关键，其直接关系到安全程度、生产效率及企业效益。根据国内外经验，结合桃花咀矿区开采技术条件、矿山现状等，提出针对厚大矿体技术可行的采矿方法有：盘区机械化上向水平分层充填采矿法、脉内顺路斜坡道上向分层充填采矿法、走向分条分层胶结充填采矿法、脉内采准机械化上向分层充填采矿法、留护壁阶段空场与上向分层联合采矿法。通过工程类比、理论分析及技术经济对比分析，确定最优的采矿方法为留护壁阶段空场与上向分层联合采矿法。现场试验及应用表明，该方法技术经济指标良好，与矿体适用性强，适于在同类型矿体及矿山推广应用，具有良好的借鉴意义。  

The selection of an appropriate mining method is critical to the survival and development of mining enterprises, directly impacting safety, production efficiency, and economic benefits. This is particularly important for mines with complex technical conditions for orebody extraction. Drawing on domestic and international experience and taking into account the mining conditions and current situation of the Taohuazui mining district, several technically feasible mining methods for thick and large orebodies are proposed: mechanized upward horizontal slicing and filling mining method for panels, in-vein ramp-along-strike upward slicing and filling mining method, strip and slicing along strike mining method and filling with cemented backfills, mechanized upward slicing and filling mining method with in-vein preliminary mining, and integrated mining method of staged open stoping with reserved  protective walls and upward slicing. Through engineering analogy, theoretical analysis, and technical and economic comparison, the optimal mining method was identified as the intergrated mining method of staged open stoping with reserved protective walls and upward slicing. Field tests and application results indicate that this method has favorable technical and economic metrics, is highly compatible with the orebody conditions, and is suitable for promotion and application in similar orebodies and mines, offering valuable references.