某大型露天采场周围的挂帮矿，约占露采境界外采矿量的 85.76 %，拟采用上向进路充填采矿法回收该部分资源。为隔离露天开采与挂帮矿地下开采的相互影响，保证高陡边坡、地下采矿作业安全，需要研究确定合理的边坡隔离矿柱厚度。西北部边坡受交汇断层的影响，稳定性较差，以该区域为研究对象，开展了相关室内试验，基于经验公式和类似矿山实际，初步确定了隔离矿柱的厚度；采用数值模拟方法进行了优选，综合边坡稳定性需要，提出了该矿山合理的边坡隔离矿柱安全厚度。结果表明：通过Flac3D软件模拟手段，结合经验公式计算结果，以及前期相关研究成果，西北部边坡隔离矿柱的合理厚度≥45 m。研究结果可为矿山设计、生产提供理论依据和参考。  

 A significant portion of the hanging ore surrounding a large open-pit mine, accounting for approximately 85.76 % of the resource beyond the open-pit boundary, is planned to be recovered using an upward drift mining and filling method. To isolate the mutual influence between open-pit and underground mining and ensure the safety of both the steep high slopes and underground operations, it is necessary to detern ea reasonabl thickness for the isolation pillars between the slope and underground stopes. Due to the influence of intersecting faults, the northwestern slope area has relatively poor stability and was selected as the study area. Laboratory tests were conducted, and initial pillar thicknesses tests were estimated based on empirical formulas and references from similar mines. Numerical simulation was then employed for optimization. Considering overall slope stability, a reasonable and safe thickness for the slope isolation pillar was proposed. The results show that, based on simulations using the Flac software, in combination with empirical calcula-tions and previous research, the optimal thickness of the isolation pillar in the northwestern slope area is >45 m. These findings provide a theoretical basis and practical reference for mine design and production.