The ore bodies are mostly steeply inclined extremely thin ore bodies in Sanhe Lead-Zinc District.The original short-hole shrinkage mining method is large in loss and dilution and  poor  in mining efficiency.Based on the long-term development goals and green mine construction requirements,the paper put forward the experimental study of joint in-vein upward slicing and resue-and-fill mining method.The stope is laid out along the strike.The ore-drawing connection roadway is excavated from the in-vein roadway to the ore vein footwall.The mining preparations are basically laid out in veins.No inter-pillars are extracted,and the mining loss rate is reduced.Part of the filling is done with tailings,which are conducive to ground pressure control.Industrial test results show that each index of joint in-vein upward slicing and resuing-and-filling mining method meets the requirements of mines.The method shows good results when mining steeply inclined extremely thin ore bodies.