The cyanidation flowsheet of Qinghai Kunlun Gold Co.,Ltd.adopts the grinding-while-leaching process.The iron powder produced in the grinding process reacts with sodium cyanide,not only causing more ball and sodium cyanide consumption but also damaging the leaching environment by generating an iron cyanide complex,hence affecting precious metal leaching.To this end,the company has carried out research on the effect of nano-composite ceramic balls on the indexes of the horizontal ball mill when the improved grinding-while-leaching process is used.The research results show that when the discharge end of the ball mill is renovated and the filling rate of nano-composite ceramic balls in ball mills,with constant ore treatment volumes,the power consumption per ton of ore is reduced by 34.90 %,the ball consumption is reduced by 56.67 %,and the sodium cyanide consumption decreases by 1.18 kg/t.The iron mass concentration in the leaching medium was significantly reduced.The medium quality was improved,and the gold leaching rate was increased by 0.23 percentage points.The annual economic benefits were increased by 2.163 4 million yuan.