To ensure the safe and efficient mining of the Xinhui Gold Mine,based on the mine-s technical mining conditions for the deep ore bodies,3 initial plans were proposed:mining with pre-reinforced pillar and upward horizontal slicing filling,upward approach filling mining,and downward approach filling mining.The analytic hierarchy process was used,and combined with the theory of fuzzy comprehensive evaluation,a multi-factor decision matrix was constructed to comprehensively consider aspects such as safety,economy,resources,and efficiency,and to score each alternative plan.Finally,the mining method of the pre-reinforced pillar and upward horizontal slicing filling was selected as the best.Through practical application,the production capacity of the stope has been improved,and production safety has been greatly enhanced.The result is consistent with engineering reality,and this method can provide a reference for the optimization of mining method selection in similar mines.