The gold grade of a gold ore in Shandong is 1.4 g/t,which belongs to low-grade gold ores.To recover valuable metals from the ore effectively,the process mineralogy of the ore was studied.The research results showed that some gold minerals in the ore existed in the form of native gold,while others existed in the form of encased gold with sulfide minerals such as pyrite.Among them,the gold minerals carried by pyrrhotite were the main reason for the loss of gold minerals due to their low monomer dissociation degree and poor natural floatability,which made them difficult to recover by flotation.Therefore,comprehensive utilization of gold minerals carried by magnetite could help improve the gold recovery rate.The flotation and tailings magnetic separation experiments were jointly conducted.The experimental results showed that increasing the grinding fineness can effectively improve the monomer dissociation degree of useful minerals;the flotation experiment can reduce the gold and sulfur grade in the flotation tailings to 0.35 g/t and 0.48  %,respectively;the tailings magnetic separation operation can reduce the gold and sulfur grade in the tailings to 0.14 g/t and 0.20 %,respectively.This research can provide references for the development and utilization of similar gold deposits.