The Seri Gold Deposit is located in the Kunzhong granite uplift belt of the East Kunlun orogenic belt and belongs to the Gouli gold polymetallic integrated exploration area. The main host rocks of the Seri Gold Deposit are Indosinian and Variscan intermediate -acidic intrusive rocks, and the mineralization is primarily controlled by NNEtrending faults. Host rock alterations include silicification, sericitization, chloritization, carbonation, and kaolinization. Based on field crosscutting relationships, the hydrothermal mineralization period is pided into 3 stages: quartz-pyrite stage, quartz-polymetallic sulfide stage, and quartz-carbonate stage. Microthermometric analysis of fluid inclusions indicates that the full homogenization and salinities are as follows: 308.50 .C-355.10 .C and 5.41 %-12.31 % during the quartz-pyrite stage, 276.90  C-312.70 C and 7.58 %-9.47 % during the quartz-polymetallic sulfide stage, and 248.30 C-286.60 C and 5.25 %-8.81 % during the quartz-carbonate stage. Comprehensive analyses suggest that the ore-forming fluid of the Seri Gold Deposit is a medium temperature, medium salinity NaCl-CO2-H,O system. C-H-O iso-topic analysis of quartz, and calcite from the mineralization stages indicates that the fluid was predominantly magmatic water, with late-stage contributions from meteoric water. In-situ S isotopic analysis shows that the ore-forming materials primarily originated from magmatic rocks. The Seri Gold Deposit is classified as a medium temperature hydrothermal vein-type gold deposit controlled by tectonics and deep magmatic activity.