To address key challenges in the ammonia⁃free thiosulfate leaching-resin adsorption gold extractionprocess, such as the easy oxidative decomposition of thiosulfate, the low stability of thiosulfate-gold complexes, and thelow efficiency of conventional activated carbon adsorption, a novel reagent system composed of leaching agent CG528,oxidant CG525, complexing agent CG524, and catalyst CG527 was developed. This system exhibits synergistic effectsamong its components, forming an efficient and stable ammonia⁃free thiosulfate leaching system. Meanwhile, a resinadsorption technique was established, whereby resin is directly added to the leaching slurry to enable simultaneousleaching and adsorption, eliminating the need for solid⁃liquid separation and achieving effective gold enrichment andrecovery. Results show that the gold leaching rate using the ammonia⁃free thiosulfate leaching-resin adsorption goldextraction process reaches 86.58 %, comparable to the cyanidation leaching rate of 86.32 %, with a gold adsorption ratefrom the solution of 95.69 % . These findings provide technical support for the industrial application of the ammo⁃nia⁃free thiosulfate leaching-resin adsorption gold extraction process.