To address the limitations in exploring concealed orebodies within the East Kunlun Orogenic Belt, acase study of the Ka’erqueka Cu polymetallic deposit was conducted. Through regional geological surveys, identification ofgeochemical anomalies, and the application of integrated prospecting technologies, the geological characteristics andmetallogenic mechanisms of the deposit were systematically analyzed, leading to the establishment of an integratedprospecting model. Results indicate that the formation of the deposit is closely related to Late Triassic-Early Jurassicintermediate-acid magmatic intrusions, with the rock mass-surrounding rock contact zone serving as the primaryore⁃controlling structure. The application of integrated prospecting technologies significantly improves explorationefficiency, achieves breakthroughs in mineral discovery, and validates the suitability of the integrated prospectingmodel for porphyry⁃type copper deposits in the East Kunlun Orogenic Belt. This study also reveals the intrinsic relation⁃ships among regional magmatic activities, tectonic evolution, and mineralization. The findings not only provide a scien⁃tific basis and practical guidance for mineral exploration in the East Kunlun Orogenic Belt but also enrich regionalmetallogenic theory, demonstrating significant academic value and potential for practical application in exploring con⁃cealed orebodies.