To address land reclamation challenges in alpinemines caused by special climate and geological conditions,including difficult vegetation restoration, scarce soil resources, and short construction periods, the De’erni CopperMine was taken as the research subject, and suitable land reclamation methods for alpine open⁃pit metal mines wereexplored to provide sustainable development examples for similar mining areas. The overview of the De’erni CopperMine and technical bottlenecks in land reclamation were analyzed. Through experimental methods including soilsimulation and pot planting, the preparation and improvement technology of serpentine slag soil and local original soilwere investigated. The optimal scheme for planting substrate was determined as a 6∶4 ratio of serpentine slag soil tooriginal soil. Through a three⁃factor three⁃level orthogonal experiment, the optimal dosages of substrate amendmentswere determined as 3.12 kg/m2 sheep manure, 1 kg/m2 humic acid, and 12 g/m2 water retaining agent. This researchestablished a reclamation model of "local slag soil utilization + amendment optimization + spray⁃seeding technology"for alpine mining areas, which can not only effectively solve land reclamation problems in alpine open⁃pit mines butalso be extended to semi⁃humid areas in North China and other construction project areas with seasonal droughtand concentrated rainfall, providing innovative ideas and practical approaches for ecological restoration of miningwastelands.