A high pyrrhotite type copper-lead-zinc polymetallic ore in Qinghai contains 35.00 % pyrrhotite and 6.00 % pyrite.Conventional flotation process can not effectively inhibit the flotation of pyrite and pyrrhotite and separate valuable elements.By adopting the magnetic separation-mixed flotation of copper,lead and sulfur-zinc recovery from tailings process,closed circuit test obtains good index: copper grade is 13.15 %,lead grade is 7.59 %,copper recovery rate is 75.10 %,lead recovery rate is 69.49 % in mixed concentrate of copper and lead;zinc grade is 48.05 %,zinc recovery rate is 76.33 % in zinc concentrate;the separation and recovery of each primary element is realized.