For a gold ore in Qinghai,based on investigation of the ore type and gold dissemination state,three processes are compared in tests including raw ore leaching by environment-friendly gold leaching agent,flotation-flotation tailings leaching by environment-friendly gold leaching agent,Nelson gravity separation-gravity tailings leaching by environment-friendly gold leaching agent.Finally,the Nelson gravity separation-gravity tailings leaching by environment-friendly gold leaching agent process is recommended.The process can lead to gold recovery rate of 97.04 %,which is easy to operate,environment-friendly and effective,the process are reliable,and can provide basics for mine development and production.