The ores in Jinchuan Mining Company belong to low-grade refractory gold ores that are hard and difficult to crush making crushers easily wear,and the gold in the ores is dominated by microfine grains resulting in low gold leaching rate averaging about 57 %.To solve these production problems,based on lab scale tests,high pressure roller mill＋cement microgranulation technology is employed,solving the wearing problems due to the ore property and greatly reducing the product grain size,improving the production capacity from 5.44 Mt/a to 6.45 Mt/a;at the same time the cement microgranulation technology is used to solve the permeability due to shrinking grain size,improving gold leaching rate by 10 percentage points,creating 121.07 million yuan more profits annually.The research can be used as reference for production process optimization in similar mines.