Copper and  lead  in cyanidation tailings are comprehensively recovered by mixed flotation process.The results show that with lime used as regulator,copper sulfate as activator,and butyl xanthate and ammonium butyrate as collector,the grades of copper,lead,gold and silver are 18.50 %,9.67 %,19.41 g/t and 850.22 g/t respectively in the mixed copper and lead concentrates obtained by the closed-circuit mixed flotation process of once roughing,twice scavenging and four times cleaning.The recoveries of copper,lead,gold and silver are 85.02 %,58.38 %,33.67 % and 69.19 % respectively.The lead concentrates with lead grade 68.40 % and copper concentrates with copper grade 20.38 % can be obtained by lead flotation and copper suppression of copper and lead mixed concentrates.The test index is ideal and the comprehensive utilization of secondary resources is realized.