According to the ore properties of a silver-bearing copper-lead-zinc polymetallic sulfide ore in Inner Mongolia,experimental research was carried out.The results show that with the partially bulk flotation process and suitable process conditions,the closed-circuit test can obtain good index:copper grade for copper concentrate 20.21 %,copper recovery rate 68.74 %,silver grade 11 772.06 g/t,silver recovery rate 29.23 %;lead grade for lead concentrate 58.64 %,lead recovery rate 90.38 %,silver grade 2 448.30 g/t,silver recovery rate 57.38 %;zinc grade for zinc concentrate 57.33 %,zinc recovery rate 86.10 %,silver grade 164.00 g/t,silver recovery rate 3.22 %;the total recovery rate of silver is 89.83 %,and copper,lead,zinc and silver are all effectively recovered.