In the case study of a silver polymetallic ore,based on a systematic mineralogy study,a small-scale test is carried out to determine optimal process flow and process conditions.The results show that when the process flow of silver lead partial preferential flotation-zinc recovery from tailings is used,grinding fineness of -0.045 mm accounts for 85 %,CG801 dosage is 2 000 g/t,CuSO4 dosage in zinc flotation is 400 g/t,and so on,good indexes are obtained.Silver and  lead  in silver lead concentrates are 14 999.71 g/t and 25.09 % respectively,silver and lead recovery rates are 87.70 % and 91.82 % respectively;silver and zinc grades in zinc concentrates are 1 398.98 g/t and 41.97 %,the silver recovery rate is 1.74 %,the zinc recovery rate is 64.12 %;total silver recovery rate is 89.44 %.