Abstract: With complex geological structure and favorable ore-forming conditions， the Genshatang area of Gansu Province is located in the middle Qinling copper-gold-lead-zinc-tungsten-molybdenum poly metallic metallogenic belt north Xiahe-Hezuo fault. 1：50000 stream sediment comprehensive anomaly is dominated by Ag， Au， As element anomalies with good fitting and obvious zonation. Based on the investigation of route reconnaissance for comprehensive anomaly， the lead-zinc-silver ore (mineralized) bodies are found to be evidently controlled by contact zone between Meiwu rock mass and wallrock， NNW-trending interlayer fracture， and closely related to silicification， tourmalinization， malachitization， gelenitization， sphaleritization and argentization. The bed rock spectral curve is presented as single peak near ore (mineralized) bodies， indicating the existence of ore (mineralized) bodies. The magnetic susceptibility of ore (mineralized) bodies are generally below 20×10^-5SI (κ)， the magnetic susceptibility is weaker in ore (mineralized) bodies than in wallrocks and displays characteristics of negative magnetic anomaly. Based on above investigation and study， prospecting model of the study area is established and through verification delineates 1 gold ore (mineralized) body and 1 lead-zinc-silver poly metallic ore (mineralized) body. The prospecting model can effectively guide further prospecting in study area.