Abstract: After thickening， the cyanide tailings pulp generated in the pressure oxidation-cyanide leaching process to treat refractory gold ores in a mine are discharged into the tailings pond in wet way， which is risky and can not meet environmental protection requirement. So the test uses 4 different processes including inco， washing， ozone and pressure oxidation solution to treat cyanide tailings pulp， compares them in terms of feasibility and comprehensive economic and technical index， and finally decides the best treatment process. The results show that the pressure oxidation solution process doesn't need additional reagent， introduces no other interference ions， and can realize the decyanation of cyanide tailings pulp.