Abstract: To improve the air cleanliness of controllable circular ventilation in deep mines and to accelerate the filtration and discharge of blasting-related dust and toxic gases, a rapid air purification system combining a micro-nano bubble water spray system and a water bath wire-carbon system was proposed. Based on a self-designed experimental platform for rapid air purification, micro-nano bubble water and atomizing nozzles were investigated to determine the optimal nozzle aperture for the best atomization performance. The dust suppression efficiency of tap water and micro-nano bubble water sprays was compared. Single-factor experiments were conducted using a wet spray fiber grid and a carbon adsorption mesh to identify optimal individual performance parameters. Finally, an optimal combination purification experiment was performed using the best-performing parameters. The results show that under the same operating conditions, a pressure fan-shaped nozzle with a 0.4 mm aperture achieved the largest atomization angle, reaching up to 90 °. The dust suppression efficiency of micro-nano bubble water was consistently higher than that of tap water, and micro-nano bubbles more effectively captured respirable dust. Wet spray fiber grids with larger apertures formed larger water films, increasing the contact area with water-soluble gases and thereby improving filtration efficiency. Thicker activated carbon fiber cotton offered more pores and a larger surface area, significantly enhancing CO adsorption. The optimal parameter combination for the rapid air purification system was as follows: micro-nano bubble water as the spray medium; high-pressure nozzles with a 0.4 mm aperture and 3 MPa water supply pressure; wet spray fiber grid using double-layer 10-mesh metal screen; and 5 mm thick activated carbon fiber cotton for the carbon adsorption mesh. Under this optimal configuration, the total dust and respirable dust removal efficiencies reached 72.83 % and 79.12 %, respectively, while the purification efficiencies for CO, H₂S, and SO₂ were 84.47 %, 78.56 %, and 55.42 %, respectively.