Abstract: To determine the reasonable stope structural parameters for the sublevel drilling stage open stope and subsequent filling mining method in Hongling Lead-Zinc Mine, numerical simulation was employed to study 16 different scenarios with roof thicknesses of 3 m, 5 m, 7 m, and 10 m, and stope lengths of 20 m, 30 m, 40 m, and 60 m, respectively. The stress, displacement, and plastic zone distribution of each scenario with a roof thickness of 3 m were compared. The results indicate that the stability of the stope in Hongling Lead-Zinc Mine is fairly good when the roof thickness is 3 m and the stope length is 35 m for the sublevel drilling stage open stope and subsequent filling mining method.