Abstract: The Greece concentrate has high arsenic grade(7.35 %),based on which experimental research is carried out on the bio-oxidation pretreatment-cyanide leaching process after the Greece concentrate is through single bio-oxidation pretreatment-cyanide leaching and blending with the Jinfeng concentrate at certain proportion.The variation status of slurry pH and redox potential with time during the bio-oxidation process is analyzed.The results show that the effect of bio-oxidation pretreatment-cyanide leaching after blending of Greece concentrate with Jinfeng concentrate(mass ratio 1∶4) is far better than that of Greece concentrate treated alone,and the bio-oxidation time is greatly reduced,the gold leaching rate of Greece concentrate is increased;plus,the pH and redox potential are higher than that of Greece concentrate treated alone,the pH value stays around 1.18,the redox potential averages at 582 mV.The research results can provide a new idea of high arsenic gold concentrate treatment.