Abstract: Experimental study on the beneficiation of a microfine disseminated gold-bearing ore with little sulfide was carried out,and all-sliming cyanidation,ultrafine grinding CIL and flotation indexes were explored.The results show that all-sliming cyanidation and ultrafine grinding CIL processes have very low gold leaching rates,4.04 % at most,so they are not suitable for treating the ore;under optimal experimental conditions,the closed-circuit test of flotation obtains good index:the gold grade of gold concentrates is 27.35 g/t,gold recovery rate is 90.63 %.The study provides reference for choosing process flowsheets for the type of ores.