Abstract: A flotation and all-sliming cyanide leaching experimental study was conducted on the ores from a gold mine with fine and unevenly distributed gold particles,mainly concentrated in the range of -0.038 mm,known as fine-grained gold.Based on the characteristics of the ores,the all-sliming cyanide leaching process was ultimately adopted,achieving favorable results.The original ore had a gold grade of 4.01 g/t,and under optimal test conditions,the gold recovery rate reached 84.29 % through all-sliming cyanide leaching,with a residue grade of  0.63 g/t.This study provides technical basis for the efficient utilization of the ores.