Abstract: According to the ore property in a gold cyanidation plant,experimental study on the replacement of sodium cyanide by environment-friendly gold leaching agent was carried out,as well as its application.The results show that under the same process flow of all-sliming cyanidation CIP,the environment-friendly gold leaching agent can totally replace sodium cyanide in production,with the gold leaching rate reaching 97.58 %,which is equal to that of sodium cyanide and lower in cost.The environment-friendly gold leaching agent has significant economic and environmental benefits.