Abstract: On account of the characteristics of one argillaceous,arsenic and carbonaceous microfine-particle disseminated refractory gold ore from Qinghai Province,experimental research to explore suitable gold extraction processes was carried out based on mineralogical study of primary ores.The results show that the combined process of flotation-flotation tailings regrinding and carbon pre-flotation-CIL can obtain good experimental index: grinding fineness of primary ores is 75.48 % -74 μm,gold grade in flotation concentrates is 35.14 g/t and gold recovery rate is 71.40 %; regrinding fineness of flotation tailings is 92.65 % -74 μm; the product goes to CIL after carbon pre-flotation; the gold leaching rate is 50.06 % using “green gold” environment-friendly gold leaching agent,and the gross recovery rate of gold is 85.72 %.The experimental index are similar to sodium cyanide leaching.