Abstract: Experimental study,including alkaline pretreatment,non-cyanide leaching while grinding and agitation leaching,is carried out on the sulfuric acid slag containing 3.55 g/t gold,0.19 % arsenic and 0.80 % sulfur in a tower mill.The results show that the leaching while grinding-agitation leaching process is suitable to treat gold-bearing sulfuric acid slag,and under the optimal conditions,with non-cyanide gold extraction agent JJC,the process can obtain good index,increasing gold leaching rate from 74.4 %,which is from conventional leaching,to 90.4 %;ultrafine grinding leaching while grinding can significantly improve gold leaching effect.The research achievement can be used as reference for the effective recovery from other gold-bearing slag and gold ores.