Abstract: The production cost is high and the treated neutralized solutions have slightly substandard environmental index when one-stage neutralization treatment is used to treat the oxidation leaching acidic solutions generated in the biological oxidation plant of Sanhe Gold Industry Co.,Ltd..Technical analysis demonstrates the feasibility of a heavy calcium carbonate＋quick lime two-stage neutralization to treat biological oxidation leaching acidic solutions.The test determines the optimal operation index of the process that is successfully applied in practice.Industrial practice shows that the two-stage neutralization process reduced the operation cost greatly,improved the environmental index of the neutralized solution,and had evident economic and environmental benefits.