Abstract: In order to further improve the recovery index of a refractory microfine-dissemination gold ore in Qinghai Province,a detailed process mineralogy study was conducted.The results showed that the main factors affecting gold recovery were the recovery of fine and micro-fine pyrite and arsenopyrite.Due to the difficulty of monomer dissociation of most fine and micro-fine pyrite and arsenopyrite during the grinding process,some gold minerals were lost.In addition,fine-grained gold inclusion by vein minerals was also an important form of gold mineral loss.It is suggested to use a flotation process with staged grinding and separation to improve gold recovery rate.