Abstract: The first mining area of a certain mine involves a gently inclined medium-thick orebody. To address the problems of small stope production capacity and low recovery rate of high-grade ore in the original design development scheme （Scheme Ⅰ）, a pseudo-inclined layout development scheme （Scheme Ⅱ） and a sub-middle section layout development scheme （Scheme Ⅲ） were proposed, and the three schemes were comprehensively compared in terms of technical and economic indicators such as panel production capacity, mining loss rate, ore dilution rate, and mining-cutting ratio. Compared with the original design development scheme, the two optimized development schemes can better adapt to the variation of orebody dip angle. The production capacities of the first mining area in Scheme Ⅱ and Scheme Ⅲ increased by 9.8 % and 6.6 %, respectively; the mining recovery rates increased from 58 % to 66 % and 78 %, respectively; moreover, Scheme Ⅲ had the lowest mining-cutting ratio. After the sub-middle section layout scheme （Scheme Ⅲ） was adopted in the first mining area of the mine, the production target was achieved ahead of schedule. The daily production capacity steadily reached 6 500 t, significantly improving the economic benefits of deposit mining.