Abstract: Refractory gold ores account for approximately two-thirds of the world’s total gold resources.In the foreseeable future,the acquisition of precious metals such as gold and silver will rely on the mining and extraction of these refractory ores.With the introduction of the concept of new quality productive forces,the traditional metallurgy industry must develop more efficient processes for production.Mineral property analysis,direct gold leaching experiments,and gold leaching tests after pressurized oxidation pretreatment were carried out on a refractory gold ore.The direct leaching experiment studied the influence of grinding fineness,leaching reagent type,and reaction time.Under the optimal experimental conditions,the gold extraction rate was 48.27 %.The pressurized oxidation pretreatment leaching test investigated the influence of factors such as  systems,temperatures,acid consumption,and retention time during the pressurized oxidation process.The optimal pretreatment conditions were found to be a concentrated sulfuric acid medium with an addition of 180 kg/t,reaction temperature of 260 ℃,oxygen partial pressure of 0.3 MPa,total pressure of 5.0 MPa,retention time of 2.5 h,and slurry concentration of 40 %,which resulted in the gold extraction rate of 84.06 %.This provides a basis for gold leaching from refractory ores.