Abstract: The gold grade is 5.08 g/t,the gold minerals are mainly inclusion gold and the grains are in uneven distribution in a microfine grain disseminated refractory gold ore.Based on the ore property,experiments of gravity,flotation and cyanidation processes are carried out.The results show that flotation alone fails to obtain satisfactory gold recovery index;gravity-gravity tailings flotation process obtains gold comprehensive recovery rate 86.45 %; gravity-cyanidation of flotation tailings of gravity tailings obtains gold comprehensive recovery rate up to 94.55 %;joint process for ore treatment is feasible and can obtain good test index.