Ejina Banner is a relatively weak area in terms of geological research on mineralization and mineral exploration in the eastern part of the Beishan Metallogenic Belt. The Laodonggou Gold Deposit is a representative gold deposit in this area, and its ore‑hosting rocks are mainly composed of the shallowly metamorphosed rock series of the Mesoproterozoic. For Laodonggou Gold Deposit and its surrounding areas, the analysis of remote sensing alteration anomalies was conducted, and remote sensing geological evidence was provided for the gold-copper polymetallic mineral exploration of Ejina Banner in eastern part of the Beishan Metallogenic Belt. Based on the Crosta characteristic principal component analysis using data from the US Landsat 8 satellite,remote sensing hydroxy alteration information and ironization alteration information were extracted.The results show that the spatial distribution of remote sensing alterationanomalies is closely related to the Triassic and Silurian granites, as well as the Qingbaikou Series of the Neoproterozoic and the Jixian Series and the Changcheng Series of the Mesoproterozoic. Based on the value level, scale, and spatial distribution of remote sensing alteration anomalies, as well as the coincidence of hydroxy alteration and ironization alteration, eight prospecting areas for the hydrothermal gold-copper polymetallic deposits and the related oxidized deposits have been delineated. Among them, there are two A‑level prospecting areas, three B‑level prospecting areas, and three C‑level prospecting areas.The analysis of remote sensing alteration anomalies confirms the strata‐bound and polygenetic compound characteristics of the Laodonggou Gold Deposit, provides a prospecting direction for gold-copper polymetallic deposits in the Laodonggou Gold Deposit and its surrounding areas, and facilitates the mineral exploration progress of Ejina Banner in eastern part of the Beishan Metallogenic Belt.