Abstract: The cyanide-containing wastewater from a gold mine is alkaline and major pollutants are total cyanide compounds and heavy metal ions. Various cyanide removal methods,including Inco process,acidification process,hydrogen peroxide oxidation,CG101-A reagent method,and electrolysis,were tested. Exploratory tests found that the Inco process and the CG101-A reagent method exhibited better cyanide removal efficiency. Further conditional tests revealed that the CG101-A reagent method is the most suitable treatment process for this wastewater. Under the conditions of a CG101-A dosage of 3 g/L (added in 3 equal portions),a reaction pH of 8-9,and a reaction time of 2 h,the total cyanide compounds removal rate reached 99.5 %. The findings provide new insights and methods for the treatment of cyanide-containing wastewater in gold mines,contributing to technological progress and environmental protection in this field.