Abstract: In light of the fact that large amounts of aeolian sands exist on the surface of the Malimuwuka area in Dulan County， Qinghai Province， 1∶25000 geochemical survey was selected for early geochemical exploration to avoid its influence. The sampling point density was 20~32 points/km². The sampling medium is sharp-cut rock debris material， medium coarse sand and remnant slope wash. The sampling granularity is -10 mesh to +60 mesh. Based on the analysis of element content， enrichment dispersion and combination characteristics， 6 geochemical exploration anomalies were delineated and 1 prospecting prospect was determined. Practice shows that 1∶25000 geochemical survey has good application value in the exploration of the alpine plateau landscape in East Kunlun.