Abstract: The gold grade is 5.08 g/t, the gold minerals are mainly inclusion gold and the grains are in uneven distribution in a micro-fine grain disseminated refractory gold ore. Based on the ore property, experiments of gravity, flotation and cyanidation processes are carried out. The results show that flotation alone fails to obtain satisfactory gold recovery index; gravity-gravity tailings flotation process obtains gold comprehensive recovery rate 86.45%; gravity-cyanidation of flotation tailings of gravity tailings obtains gold comprehensive recovery rate up to 94.55%; joint process for ore treatment is feasible and can obtain good test index.