Abstract: In light of the high total cyanide and arsenic content in the cyanide tailings of a gold concentrate smelting enterprise,joint hydroperoxide oxidation and ferrous salt precipitation process is used to carry out detoxification treatment and the test conditions are optimized.The optimal test parameters are:hydroperoxide dosage is 2.0 mL/L,pH is 6.0-6.5,reaction time is 2 h for the cyanide detoxification phase;ferrous sulfate heptahydrate dosge is 0.50 g/L,hydroperoxide dosage is 1.0 mL/L,pH is 6.0-6.5,reaction time is 1 h for the arsenic detoxification phase.The mass concentrations of total cyanide and arsenic in the toxicity leaching solution from the cyanide tailings pulp filter are both lower than the tailings pond disposal standards according to HJ 943—2018 Technical Specification for Pollution Control of Cyanide Leaching Residue in Gold Industry,and the tailings can be stockpiled in the tailings pond.